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==Description==
When boys are born, the preputial sac is sealed shut by a [[synechia]] called the ''balanopreputial lamina'', so it cannot be infected. The preputial sac will remain closed for a variable number of years.
The preputial sac is lined with [[mucosa]] as is appropriate for an internal organ where moisture is present.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> Urine and other sources of moisture are not harmful to it.