Pain

The pain of circumcision is extreme and traumatizing. Infant boys cry a special cry of distress. Ostwall & Peltzman (1974) noted:

“

Our attention has been focused on the distress cry of infants. We have recorded numerous distress cries resulting from routine medical procedures such as taking blood samples and minor surgery such as circumcision. The distress cry is louder, longer, and noisier than the hunger cry. In also tends to be irregular, with more interruptions and gagging. – Ostwall & Peltzman (1974)

Infant circumcision

Intraoperative pain

Circumcision is most-commonly performed on newborn infants as a non-therapeutic cultural body re-configuration. At that tender age, the foreskin normally is fused with the underlying glans penis by a synechial membrane that is common to both parts. Winkelmann (1956) stated the human newborn prepuce "is a region of great sensitivity and possessed of an abundant nerve supply."

There are four painful steps in every infant circumcision:

1. Before circumcision surgery can commence, the surgeon must first forcibly separate these two highly innervated body parts in an exquisitely painful procedure by forcing a blunt probe between the two parts to destroy, rip and tear the synechia apart.
2. Next, in another painful step, a dorsal slit must be cut in the foreskin, so that a special clamp can be installed.
3. The foreskin is erogenous tissue, so it is highly innervated. Nervous tissue requires a large blood supply, so the foreskin is richly vascularized with many blood vessels, therefore the foreskin must be crushed with one of several special clamps in yet another painful step before the circumcision can be carried out.
4. Finally, in another, painful step, the foreskin must be cut away.

Lander et al. (1997) conducted a comparison neonatal non-therapeutic circumcision without anesthesia (current practice in 1997), ring block, dorsal penile nerve block, and a topical eutectic mixture of local anesthetics (EMLA).

With no anesthesia, the infants screamed continuously. Newborns in the untreated placebo group exhibited homogeneous responses that consisted of sustained elevation of heart rate and high pitched cry throughout the circumcision and following. Two newborns in the placebo group became ill following circumcision (choking and apnea). One experienced projectile vomiting.

EMLA was the least effective pain control. Dorsal penile nerve block (DPNB) was more effective, and ring block was the most effective. The authors reported "[w]ithout exception, newborns in this study who did not receive an analgesic suffered great distress during and following the circumcision, and they were exposed to unnecessary risk (from choking or apnea)." The authors were so alarmed that they terminated the no anesthesia arm of the study early.

None of the analgesic measures tested provided total pain relief. Any infant boy who undergoes neonatal circumcision will experience some pain and trauma. Boys who escape circumcision would have no pain or trauma. The authors concluded that circumcision should be performed with anesthetic, however the text makes clear that they meant analgesia, since full anesthesia is unsafe for neonates.

Post-surgical pain

Circumcision is an invasive cutting and amputation. Like other invasive operations, post-surgical pain persists after the surgery for days or weeks. Infant boys will not receive effective analgesia because their young age makes such drugs dangerous.

Howard et al. (1994) studied male infants after their neonatal circumcision. They recorded the comfort scores of the infants at numerous periods after circumcision. They also observed and recorded feeding behavior.

It was found that feeding behavior deteriorated significantly after circumcision. Some breastfed infants were unable to breastfeed and required formula feeding after circumcision. Acetaminophen was found to be almost totally ineffective against the post-circumcision pain. It did have some effect six hours after the circumcision. The authors concluded "that circumcision of the newborn causes severe and persistent pain."

Parents who choose to have a son circumcised may expect the infant boy to be uncomfortable and fussy for some time. The surgical pain may be expected to last for three weeks.

Traumatic effect of infant circumcision

When an infant boy is to be circumcised, it is the usual practice to immobilize the infant for the painful surgery by securely tying his limbs to a molded plastic board, called the Circumstraint, specially made for that purpose. The infant thus is preventing from fighting or fleeing, which is the trauma-producing situation of inescapable shock, described as a "physical condition in which the organism cannot do anything to affect the inevitable."

There is now substantial evidence that the extreme pain of infant circumcision causes post-traumatic stress disorder ̪(PTSD). Preverbal memory starts to function before birth and continues to function in the newborn period, and infants are now known to feel pain intensely, so all of the necessary requirements are present.

Bellini observed that circumcised boys evidently remember pain. Taddio & colleagues (1995)(1997) studied the effect of neonatal circumcision on the behavior of boys after surgery and at the time of vaccination. It was found that circumcised boys had a higher pain response at time of vaccination six months later as compared with intact boys, showing that the nervous system had been permanently sensitized to heightened pain sensation.

Taddio et al. (1997) concluded:

“

Although postsurgical central sensitisation (allodynia and hyperalgesia) can extend to sites of the body distal from the wound, suggesting a supraspinal effect, the long-term consequences of surgery done without anaesthesia are likely to include post-traumatic stress as well as pain. It is, therefore, possible that the greater vaccination response in the infants circumcised without anaesthesia may represent an infant analogue of a post-traumatic stress disorder triggered by a traumatic and painful event and re-experienced under similar circumstances of pain during vaccination. – Taddio et al. (1997)

John Rhinehart, M.D. (1999), a clinical psychiatrist, reported finding numerous cases of PTSD in his adult male patients pursuant to infant circumcision.

History

Investigating pain of circumcision

Paul Emil Flechsig (1847-1929) was an eminent nineteenth-century German neuroanatomist, psychiatrist and neuropathologist. He suggested in 1872 that infants could not feel pain because their nerves are not completely myelinated. Incredible as it may seem today, his idea was accepted without question and without being tested.

As a result, medical doctors performed all manners of invasive, painful procedures on neonates without anesthesia or analgesia, including millions upon millions of painful circumcisions and even open heart surgery. Open heart surgery was performed with curare to paralyze the infant but without any anesthesia.

Flechsig's bizarre opinion was not questioned until the 1970s. Several lines of empirical research carried out in the 1970s suggested that infants can in fact feel intense pain.

• Anders et al. (1970) showed that measurement of serum cortisol is a useful indicator of pain for psychological investigation in infancy.

• Emde et al. (1971) showed that the "stress" of circumcision caused an increase in the amount of non-REM sleep.

• Richards, Bernal & Brackbill (1976) reported behavioral differences between American boys (circumcised) and British boys (genitally intact).

• Luther, Kraybill & Potter (1976) compared the level of cortisol in infants before and after circumcision. They found a substantial rise in the cortisol levels in the infants, which they said was due to the "stress" of circumcision.

• Rawlings, Miller & Engel (1980) showed that as the pain of circumcision increased, oxygenation of the skin decreased.

• Gunnar et al. (1981) recorded serum cortisol and behavior state throughout the unanesthetized, non-therapeutic circumcision process. Serum cortisol levels and behavioral distress were found to be closely related. The authors stated:

“	Neonatal circumcision is performed without anesthesia and it is clearly stressful for the infant. – Gunnar et al. (1981)

So great was Flechsig's influence, the authors were still unwilling to use the word pain and substituted the word stress.

• Marshall et al. (1982) studied mother-child interaction with regard to feeding behavior after circumcision without anesthesia. They found that circumcised boys had more interruptions of feeding in the 24-hour period of observation.

Porter, Miller & Marshall (1986) studied the nature of pain cries during unanesthetized, non-therapeutic circumcision. the cries during circumcision were found to shorter, with more more frequent vocalizations; higher peak fundamental frequencies; fewer harmonics; and greater variability of the fundamental. Adult listeners judged these cries to have an unusual degree of urgency.

Surgical operation on infants without anesthesia continued for well over a century, at least until 1987, when the American Academy of Pediatrics was forced to issue a CYA statement that called for the use of anesthesia.

Anand & Hickey (1987) published a paper in the New England Journal of Medicine that totally demolished Flechsig's ridiculous claims and conclusively proved that newborn infants are capable of feeling intense pain. After publication of this paper, no doubt about pain sensation in infants remained. The article stated:

“

Numerous lines of evidence suggest that even in the human fetus, pain pathways as well as cortical and subcortical centers necessary for pain perception are well developed late in gestation, and the neurochemical systems now known to be associated with pain transmission and modulation are intact and functional. Physiologic responses to painful stimuli have been well documented in neonates of various gestational ages and are reflected in hormonal, metabolic, and cardiorespiratory changes similar to but greater than those observed in adult subjects. Other responses in newborn infants are suggestive of integrated emotional and behavioral responses to pain and are retained in memory long enough to modify subsequent behavior patterns. – Anand & Hickey (1987)

Gunnar et al. (1988) examined the association between behavioral distress and adrenocortical activity. It was found that differences in behavioral distress did not reliably the level of adrenocortical activity. Moreover, it was found that while non-nutritive sucking reduces crying it did not reduce the adrenocortical response to the stressful stimulus of circumcision pain.

Although by 1989 it was totally clear that infants can feel intense pain, the American Academy of Pediatrics Circumcision Task Force, under the leadership of the infamous Edgar J. Schoen, M.D., declined to recommend the use of analgesics for non-therapeutic neonatal circumcision, thereby condemning millions of newborn baby boys to a painful, stressful, traumatizing circumcision.

Finding an ethical way to do painful non-therapeutic circumcision

The financially and psychologically vested circumcision industry suddenly found itself in a predicament. It was now suddenly proven beyond any shadow of a doubt that newborn baby boys can feel intense pain. Medical ethics and the standard of care now necessitated pain relief, however it is dangerous to give general anesthesia to neonates. Edward Wallerstein (1985) had proposed that routine (non-therapeutic) circumcision of baby boys be eliminated just as routine tonsillectomy and adenoidectomy previously had been eliminated, however this clearly would not do for the avid pro-circumcision lobby. No circumcision equals no fee for surgery. The financial gain from discontinuing non-therapeutic circumcision is just too high to discard. Dan Bollinger (2012) estimated that the total annual cost of non-therapeutic circumcision to Americans is $3,647,000,000. The avaricious American circumcision industry is simply not willing to give that lucrative income up, so a way to make non-therapeutic circumcisions in infancy acceptable had to be found.

Three methods were proposed:

• Application of EMLA Cream topical anesthetic. EMLA is a eutectic mixture of lidocaine 2.5% and prilocaine 2.5%. EMLA Cream (lidocaine 2.5% and prilocaine 2.5%), applied to intact skin under occlusive dressing, provides dermal analgesia by the release of lidocaine and prilocaine from the cream into the epidermal and dermal layers of the skin and by the accumulation of lidocaine and prilocaine in the vicinity of dermal pain receptors and nerve endings.

• Dorsal Penile Nerve Block (DPNB) as proposed by Kirya & Werthman (1978).

• Ring Block. Broadman et al. (1987) proposed ring block for neonatal non-therapeutic circumcision. Ring block is considered the most effective analgesic procedure for neonatal non-therapeutic circumcision. Infant boys feel less pain and suffer less trauma than with the other two pain reduction procedures.

However, none of the above three procedures totally eliminate pain. A baby boy will still experience some pain and trauma despite any of those analgesic procedures. Prevention of pain requires protecting a boy from elective neonatal non-therapeutic circumcision. Only boys who are protected from the medically unnecessary circumcision surgery experience no pain or trauma.

Wallerstein (1985) and Van Howe & Cold (1998) have suggested that it would be better to abandon the practice of non-therapeutic infant circumcision because of the pain associated with it.

The Daily Mail (2021) reported the pain stress of non-therapeutic neonatal circumcision increases the risk of SIDS, and that the incidence of Sudden Infant Death Syndrome (SIDS) is lower where baby boys are not circumcised.

The pain that infant boys experience would not be acceptable in older boys and adults. It is not clear why infant boys are still subjected to a lesser standard of care with regard to pain than older boys and adults.

Attitudes and practices regarding analgesia for newborn circumcision

Historic attitudes and practices

Wellington & Rieder (1993) conducted a survey of physicians in London, Ontario. They found that only 4 percent used DPNB. They concluded:

“

Despite evidence that neonates perceive pain and that there is a physiologic stress response to circumcision which can be reduced if analgesia is employed, the vast majority of physicians performing newborn circumcisions either do not employ analgesics or employ analgesics of questionable efficacy. Lack of familiarity with the use of analgesics among neonates and with dorsal penile block in particular are the most common reasons cited for lack of analgesic use. Educational efforts and research into less invasive techniques of analgesia for newborn circumcision are urgently required. – Wellington & Rieder (1993)

Ryan & Finer (1994) carried out a training program for physicians in the newborn nurseries of the Womens' Pavilion, Royal Alexandra Hospital, Edmonton, Alberta, Canada. After a training program, they found that 66 percent of physicians who perform non-therapeutic neonatal circumcisions had started to use analgesia during the procedure. This applies to one hospital in Canada. (Non-therapeutic neonatal circumcisions are no longer performed in most Canadian hospitals.)

Maxwell & Yaster (1999) called on physicians to use analgesia during neonatal non-therapeutic circumcision surgery, saying:

“

DESPITE THE DEBATE that continues over the benefits and risks of nonritual neonatal circumcision, it remains a commonly performed surgical procedure in the United States. To the best of our knowledge, it is the only surgical procedure that is routinely performed without first administering analgesia or anesthesia. This unconscionable state of affairs exists, despite the overwhelming evidence that newborns, even those born prematurely, are capable of experiencing pain. Indeed, anyone present during a circumcision realizes that the newborn feels and responds to pain and will attempt to withdraw if unrestrained. In addition, this pain has physiologic correlates: elevated heart rate and blood pressure, lowered arterial oxygen saturation, and elevated levels of adrenocortical hormones. During the past 15 years, results of a multitude of studies have demonstrated that effective analgesia can prevent this pain and ameliorate the associated stress response. Furthermore, the failure to provide anesthesia or analgesia has been shown to cause not only short-term physiologic perturbations but also longer-term behavioral changes. – Maxwell & Yaster (1999)

The American Academy of Pediatrics convened a new task force on circumcision under the chair of Carole M. Lannon, M.D.. That task force reversed the position previously taken under Edgar J. Schoen. It clearly stated that non-therapeutic infant circumcision is "not essential to the child’s current well-being." It provided an extensive discussion of procedural analgesia and said, quite strongly, that, if a circumcision is done, procedural analgesia should be provided.

Kraft (2003) reported that "many health care practitioners routinely perform this procedure without the use of any or with inadequate or ineffective analgesia and anesthesia."

Contemporary attitudes and practices

Little is known about current attitudes and practices regarding the use of analgesia in circumcision of the newborn. Application of analgesia prior to neonatal nontherapeutic circumcision takes additional physician time, so there may be a tendency to skip it.

Standard of care

It is now clear that boys are born with a healthy foreskin without evidence of disease. Therefore there are no indications for infant circumcision, which is a non-therapeutic and medically-unnecessary surgical operation. Circumcision excises the highly functional foreskin, which provides numerous protective, immunological, sensory, and sexual functions, so it is an irreversible, lasting injury. Bellini (2022) considered that the pain of neonatal circumcision "can have long term consequences for the developing child." Non-therapeutic circumcision of male minors is not the standard of care.

Nevertheless, some non-therapeutic circumcisions of boys will continue to be performed for religious reasons, ethnic reasons, and the emotional needs of parents. When a circumcision is to be performed, the standard of care requires that analgesia be provided to reduce the extreme level of pain and trauma. (Total anesthesia cannot be used with infants.) The Australian Association of Paediatric Surgeons (AAPS) (1996) opposed the practice of infant circumcision, but recognized that it would be performed for religious, cultural, or family reasons, in which case, the non-therapeutic circumcision should be deferred for six months, so that general anesthesia may be used. The AAPS stated:

In this event the procedure should be performed electively after six months of age. When performed, it should be carried out by a surgeon performing circumcisions on children on a regular basis with an anaesthetist using appropriate techniques. This would imply that the anaesthetist is fully trained in the art of paediatric anaesthesia, including the ability to perform caudal and penile regional or local anaesthesia. The operation should be carried out in a paediatrically orientated environment, designed to reduce the risk to the child and providing support to the parents or caregivers.

The practice of non-therapeutic circumcision of boys has nearly died out in Australia.

Pain's injury to the infant nervous system

Anand & Hickey (1985) conclusively demonstrated that infants feel pain and feel it more intensely than adults.

Pain researcher Maria Fitzgerald (1998) reported the sensitivity of the infant nervous system to extreme pain:

We and others have established that the developing nervous system is even more vulnerable to injury than in adults and that changes to the pathways induced shortly after birth can become permanent. This is because newborn nerve damage not only results in the death of sensory nerve cells, but causes other sensory nerve terminals to sprout extensively and occupy areas normally exclusively devoted to the damaged nerve.

Several later researchers suggested that extreme pain in the newborn could cause neurological injury. Anand & Scalzo (2000) concluded:

“

The public health importance of abnormal stimulation during the neonatal period cannot be overemphasized. While programs for formulating appropriate health policies and public education campaigns must disseminate this message, it is also important for these effects to be investigated, particularly with a view to developing effective therapeutic strategies for the growing children and adolescents who were exposed to abnormal conditions during the neonatal period. – Anand & Scalzo (2000)

Fitzgerald & Walker (2003) argued that extreme pain (such as that caused by circumcision) may alter developing nervous tissue in the very young.

Tye & Sardi advised:

Thus, while there is literature that addresses the ways in which pain experienced by neonates not only has negative short- and long term psychological consequences, policy making documents on neonatal circumcision do not address the fact that such pain is not adequately nor regularly controlled for during the procedure, and that failure to control for pain can have lasting effects on the child, possibly into adulthood.

Videos

Infant circumcision procedure

This is a video of an actual infant circumcision. It has a sound tract so one can hear the comments of the doctor and the sounds made by the infant. The doctor gives an injection of local anesthetic that apparently does not stop any pain at all. The infant goes silent at about 6:15 on the video, so he may have gone into shock at that time. Not for the squeamish:

• Trained medical professionals restrain infant to amputate part of its body while baby kicks and screams in pain. Retrieved 11 March 2022.

• Circumcision video

Here is an infant circumcision video of an Islamic circumcision from the Russian Federation. The surgical technique is different but the pain is no less:

Here is a video of Dr. Paul Fleiss speaking about the harm of circumcision, including pain and trauma.

Ronald Goldman

Ronald Goldman discussed pain and trauma in a video by Brendon Marotta:

Adolescent and adult circumcision

Adolescent and adult circumcision is usually carried out under total anesthesia, either by local or regional nerve block or by general anesthesia, so the pain of the surgery is not usually a concern. That does not mean that the operation is pain free. It is not pain free.

• There is, of course, post-surgical pain, which may be relieved by a potent oral analgesic. One should have a two-week supply of analgesic medicine.

• The recovery period for adolescent and adult circumcision is usually placed at six weeks. During that period of time, many patients experience pain when they they have involuntary nocturnal erections and the erection tightens the residual skin and pulls at the incision and suture. In a few cases, the erections may cause wound dehiscence which requires additional surgery to re-close the surgical wound.

• That is not the only source of pain. Circumcision amputates the protective foreskin. In cases of phimosis, the glans penis may never have been exposed before, so there frequently is severe pain when the glans penis touches anything. Many men complain that they are unable to wear trousers for an extended period of time. Only time and keratinization can ease this pain.

• Circumcision is inexact surgery. Surgeons have to guess at how much skin to amputate, so they frequently get it wrong. If sufficient skin is not available to permit penis expansion during times of erection, then taut, painful erections are the result. This complication may be treated by tissue expansion. The tension may also cause wound dehiscence, which would cause additional pain.

• Neuromas may form at the circumcision scar. Cold & Taylor (1999) reported that they are "notorious for generating pain.".

See also

• Circumstraint
• Does Cosmetic Surgery Harm Babies?
• Post-traumatic stress disorder
• Psychological issues of male circumcision
• Shock
• Sudden Infant Death Syndrome
• Trauma

External links

• Hill, George (11 September 2006). Pain of circumcision and pain control, Circumcision Reference Library. Retrieved 8 November 2020.
  Quote: Circumcision is the most stressful surgical procedure commonly performed on newborns.
• American Academy of Pediatrics. The assessment and management of acute pain in infants, children, and adolescents. Pediatrics. September 2001; 108(3): 793-7. PMID. DOI. Retrieved 17 November 2020.
• Bellieni CV. Neonatal Infant Pain Scale in assessing pain and pain relief for newborn male circumcision . Int J Impot Res. May 2023; 35(3): 282-5. PMID. DOI. Retrieved 9 October 2023.
• Tinari, Paul D. (2008). MRI Studies: The Brain Permanently Altered From Infant Circumcision, Peaceful Parenting. Retrieved 22 October 2021.
  Quote: A neurologist who saw the results to postulated that the data indicated that circumcision affected most intensely the portions of the victim's brain associated with reasoning, perception and emotions. Follow up tests on the infant one day, one week and one month after the surgery indicated that the child's brain never returned to its baseline configuration. In other words, the evidence generated by this research indicated that the brain of the circumcised infant was permanently changed by the surgery.
• (21 April 2015). Babies more sensitive to pain than adults, http://www.circinfo.org/, Oxford University News. Retrieved 18 March 2021.
• Young, High (2014). Circumcision and Pain. Retrieved 17 October 2021.
• Chapin, Georganne (13 February 2016). American Academy of Pediatrics: End the Pain, Intact America. Retrieved 2 April 2021.
• Carpenter LM. If You Prick Us: Masculinity and Circumcision Pain in the United States and Canada, 1960–2000. Gender & History. 25 March 2020; 31(1): 54-69-. DOI. Retrieved 24 August 2022.
• Anonymous. The pain that never goes away., Google. Retrieved 18 August 2023.
• Garrett, Connor (2 February 2024). A Timeline of Circumcision Suffering: A Detailed Look, Intact America. Retrieved 9 February 2024.