Circumcision and HIV: Difference between revisions

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Boyle & Hill (2011) have shown these RCTs to be have significant methodological flaws and statistical errors that render their claims invalid. Although a 60 percent ''relative'' reduction in [[HIV]] was claimed, the ''absolute'' reduction was a statistically insignificant 1.3 percent.<ref name="boyle-hill2011">{{BoyleGJ HillG 2011}}</ref>
Boyle & Hill (2011) have shown these RCTs to be have significant methodological flaws and statistical errors that render their claims invalid. Although a 60 percent ''relative'' reduction in [[HIV]] was claimed, the ''absolute'' reduction was a statistically insignificant 1.3 percent.<ref name="boyle-hill2011">{{BoyleGJ HillG 2011}}</ref>


Concerns about the three randomized controlled clinical trials (RCCTs) in Africa (in South Africa, Uganda, and Kenya)<ref>{{REFjournal
Concerns about the [[HIV trials in Africa|three randomized controlled clinical trials (RCCTs) in Africa]] (in South Africa, Uganda, and Kenya)<ref>{{RCT Auvert et al 2005}}</ref><ref name="bailey2007">{{RCT Bailey et al 2007}}</ref><ref name="gray2007">{{RCT Gray et al 2007}}</ref>:
|last=Auvert
|init=B
|author-link=Bertran Auvert
|last2=Taljaard
|init2=D
|last3=Lagarde
|init3=E
|last4=Sobngwi-Tambekou
|init4=J
|last5=Sitta
|init5=R
|last6=Puren
|init6=A
|title=Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 trial
|journal=PLoS Med
|date=2005
|volume=2
|issue=11
|page=e298
}}</ref><ref name="bailey2007">{{RCT Bailey et al 2007}}</ref><ref name="gray2007">{{RCT Gray et al 2007}}</ref>:
* The three RCTs were terminated early because results had reached a signifıcent level showing reduced [[HIV]] infections in experimental compared with control groups; however, it was too soon to gauge long-term effectiveness.
* The three RCTs were terminated early because results had reached a signifıcent level showing reduced [[HIV]] infections in experimental compared with control groups; however, it was too soon to gauge long-term effectiveness.
* The results have no relevance for women or for men who have sex with men.
* The results have no relevance for women or for men who have sex with men.